Dietary management is important for patients with chronic kidney disease, but this should not be interpreted simply as “eating as little as possible.” Excessive restriction can prevent adequate intake of calories and essential nutrients, leading to muscle loss, reduced physical function, vulnerability to infection, and frailty.
Conversely, this does not mean that protein or sodium can be consumed without restriction. The key is to distinguish between what should be restricted and what should be consumed adequately according to the stage of kidney function, dialysis status, blood test results, comorbidities, and nutritional status.
Key Conclusion: What Is Restricted Matters More Than the Overall Amount of Food
A chronic kidney disease diet has two distinct goals.
- Adjust sodium, protein, and other nutrients within the necessary range to reduce the burden on the kidneys and metabolic abnormalities.
- Provide sufficient energy and nutrients to maintain body weight, muscle, and physical activity.
Focusing on only one goal can cause problems. Excessively reducing the types and amounts of food can lead to insufficient calorie intake, causing even the protein consumed to be used as an energy source. Conversely, indiscriminate consumption of high-protein meals, salty foods, and processed foods can make kidney disease more difficult to manage in some patients.
Therefore, the term individualized balanced diet is closer to the actual principle than “restrictive diet.”
Why Eating Less Leads to Muscle Loss
When Calories Are Insufficient, the Body Breaks Down Stored Tissue
When food does not provide enough energy, the body breaks down not only fat but also muscle protein to obtain energy and amino acids. If protein intake has also been reduced, it becomes even more difficult to replace these losses.
In chronic kidney disease, the following factors can further accelerate muscle loss:
- Poor appetite, nausea, or changes in taste
- Inflammation and infection
- Metabolic acidosis
- Reduced physical activity
- Comorbidities such as diabetes or cardiovascular disease
- Nutrient losses and metabolic burden during dialysis
- Overly complex dietary restrictions
Protein-Energy Wasting Is Not Simply Being Underweight
“Protein-energy wasting,” as used in kidney disease, refers to a state in which the body’s stores of protein and energy have decreased. It is assessed comprehensively based not only on weight loss but also on loss of muscle mass, reduced food intake, low body mass index, and certain blood markers.
When edema is present, fluid can make body weight appear stable or increased even while muscle is being lost. Therefore, nutritional status should not be assumed to be adequate based on the number on the scale alone.
Protein Restriction Is Not the Same Prescription for Everyone
International guidelines generally recommend that patients with chronic kidney disease who are not on dialysis avoid excessive high-protein intake. The KDIGO 2024 guideline suggests a protein intake of approximately 0.8g per kilogram of body weight per day for adults with stage 3–5 chronic kidney disease and advises adults at risk of progression to avoid high protein intake exceeding 1.3g per kilogram per day.
However, these numbers are not an individual prescription. Actual requirements vary depending on age, body size, nutritional status, diabetes, inflammation, physical activity, pregnancy status, and dialysis status. In people with obesity or edema, current body weight may not be used directly in the calculation.
When a Low-Protein Diet May Be Appropriate
For some metabolically stable patients who are not on dialysis, a lower-protein diet may be used under the supervision of medical and nutrition professionals. In this case, sufficient calories must be ensured, and nutritional status and blood test results must be continuously monitored. A patient arbitrarily reducing both rice and side dishes is not the same as following a guideline-based low-protein diet.
Conditions Change After Dialysis Begins
During hemodialysis or peritoneal dialysis, protein loss and catabolism may occur, so protein requirements are generally higher than for patients who are not on dialysis. Continuing the same low-protein diet followed before dialysis may result in insufficient intake, so the diet must be readjusted according to the prescription from the dialysis center.
What Should Be Adjusted for Each Nutrient?
| Item | Basic principle | Problems caused by excessive restriction | Why individualization is needed |
|---|---|---|---|
| Total calories | Ensure enough to maintain weight and muscle | May cause weight loss, muscle breakdown, fatigue, and frailty | Age, activity level, body size, and weight goals differ |
| Protein | Patients not on dialysis should avoid excess and meet the prescribed amount | Excessive restriction can reduce muscle and physical function | Stage of kidney disease, nutritional status, and dialysis status are important |
| Sodium | Reducing salty foods and processed foods is generally recommended | If food becomes too unpalatable, overall intake may decrease | Blood pressure, edema, heart failure, and medications must be considered together |
| Potassium | Adjust food sources when blood potassium is high or there is a risk of it rising | Unnecessary restriction reduces intake of fruits, vegetables, and dietary fiber | Medications, acidosis, constipation, blood glucose, and residual kidney function also have an effect |
| Phosphorus | Adjust according to blood phosphorus levels and food sources | Avoiding all protein foods can cause nutritional deficiencies | Phosphate additives and animal- and plant-based sources have different absorption rates |
| Fluids | Follow the target amount when fluid restriction is prescribed by the medical team | Unnecessary restriction can increase the risk of dehydration | Requirements vary according to urine output, edema, heart failure, and dialysis method |
Daily energy requirements in nutrition guidelines are often individualized within a range of approximately 25–35kcal per kilogram of body weight, but this is not a prescription for self-calculation. Requirements vary according to age, activity level, weight changes, and disease status, and a professional must also determine which body weight should be used for the calculation.
Why Potassium and Phosphorus Should Not Be Avoided Unconditionally
Potassium Should Be Assessed Alongside Test Results and Causes
Reduced kidney function can make potassium excretion more difficult, but not every patient with chronic kidney disease develops hyperkalemia. Blood potassium can also be affected by certain blood pressure medications, metabolic acidosis, constipation, blood glucose control, and errors during the testing process.
If test results are normal, broadly eliminating fruits and vegetables can lead to inadequate dietary fiber and vitamin intake and reduced dietary variety. If potassium is high, the actual sources should first be identified, followed by adjustments to food types, amounts, and cooking methods.
For Phosphorus, the Absorbed Form Matters as Well as the Amount
Processed meats, processed cheese, instant foods, and some beverages may contain phosphate additives. Phosphorus in additive form is absorbed relatively well. Phosphorus in plant-based foods is present in the form of phytate and tends to have a lower absorption rate.
Therefore, rather than eliminating all protein foods to reduce phosphorus, it is necessary to check ingredient lists for phosphate additives and compare both nutritional value and absorption rates.